Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report
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چکیده
منابع مشابه
Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report
UNLABELLED We present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia. He had a 13-month history of bone pain involving his shoulders, hips, and knee. He received adefovir dipivoxil for treatment of lamivudine-resistant hepatitis B virus infection for 5 years before the occ...
متن کاملPathologic Femoral Neck Fracture Due to Fanconi Syndrome Induced by Adefovir Dipivoxil Therapy for Hepatitis B
In Fanconi syndrome, hypophosphatemic osteomalacia is caused by proximal renal tubule dysfunction which leads to impaired reabsorption of amino acids, glucose, urate, and phosphate. We present a rare case of a 43-year-old Korean male who was found to have insufficiency stress fracture of the femoral neck secondary to osteomalacia due to Fanconi syndrome. He had been receiving low-dose adefovir ...
متن کاملBilateral femoral head necrosis and pathological fractures resulted from Fanconi syndrome due to adefovir dipivoxil treatment: a case report and systematic analysis of 7 cases
We presented a case of a patient underwent bilateral total hip arthroplasty for femoral head necrosis and pathological femoral neck fracture resulted from adefovir dipivoxil related Fanconi syndrome. Then, we ran a systematic analysis of seven similar cases. Surgical treatment was used in three cases, while no surgical treatment was conducted in the other four. Satisfactory clinic outcome was a...
متن کاملInsufficiency fractures related to low-dose adefovir dipivoxil treatment for chronic hepatitis B.
We present a case of a 53-year-old woman who developed multifocal insufficiency fractures associated with adefovir dipivoxil (ADV) induced osteomalacia, including recurring metatarsal insufficiency fractures and a subtrochanteric femoral insufficiency fracture requiring surgical fixation. She had received low-dose ADV treatment for 59 months for chronic hepatitis B viral infection at the time o...
متن کاملAdefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B.
BACKGROUND In preclinical and phase 2 studies, adefovir dipivoxil demonstrated potent activity against hepatitis B virus (HBV), including lamivudine-resistant strains. METHODS We randomly assigned 515 patients with chronic hepatitis B who were positive for hepatitis B e antigen (HBeAg) to receive 10 mg of adefovir dipivoxil (172 patients), 30 mg of adefovir dipivoxil (173), or placebo (170) d...
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ژورنال
عنوان ژورنال: Diagnostic Pathology
سال: 2012
ISSN: 1746-1596
DOI: 10.1186/1746-1596-7-108